You will have to build your T-SQL statement for each constraint that you want to drop. There are undocumented procedures that could be used for this like sp_MSforeachtable, but I am not to fond of using them. However, SQLUSA.com provides this as an example:
-- SQL disable all constraints - disable all constraints sql server
EXEC sp_MSforeachtable @command1="ALTER TABLE ? NOCHECK CONSTRAINT ALL"
GO
Another option was provided here on SO, by Aaron Bertrand.
Then if you like PowerShell you could do something like this (forum located on SQLServerCentral.com), provided by Rob Farley:
#This is one line just broken up for readability.
PS SQLSERVER:\sql\localhost\default\Databases\YourDatabase>
dir Tables\*\Columns\*\DefaultConstraint
| % {$_.Script(); $_.Drop()}
And if you want a few more examples check here.