The cluster manager software can help make a lot of operational tasks much simpler, and can avoid mistakes such as restarting machines in the wrong order for a rolling upgrade or so on. There is also a competing product from SeveralNines which is said to be superior in some respects, although I can't comment more on that because I haven't used it.
Why would you want some kind of cluster management software? Can you live without it? Yes, you can. But do not underestimate the complexity of administering a MySQL cluster based on NDB technology. It is NOT just a storage engine for MySQL, and it is NOT related to or similar to standard MySQL. It is a set of MySQL servers with a storage engine acting as a front-end or proxy to a completely separate NDB database, and NDB is probably unlike anything you've administered before. It's also not really compatible with standard MySQL from the behavioral point of view, so you will have to build your application to work with/around its characteristics; an NDB cluster migration commonly involves a significant application rearchitecture project.
If you don't really know what you are doing, you will probably not achieve whatever your goals are (high availability, high durability, high performance). Fat-finger something and you can cause downtime or even complete data loss. A "good" administrator usually has years of experience with it. No offense, but the fact that you need to ask what the cluster manager software does for you probably indicates that you're not knowledgeable enough -- I would be scared if I were you. NDB is not simple; take a look at the number of lines of code and compare that to MySQL; now compare the size of the user manual and the size of the userbase, and consider that you're getting into a very specialized field with not enough documentation, only a few gurus, and not a huge population of administrators with a very large shared knowledge.
The reason someone mentioned Percona XtraDB Cluster is likely because it's basically standard MySQL with standard InnoDB, with a cluster communication component to replace standard replication with something better, called Galera. I work for Percona, and I'm not trying to boost it, only adding a little context to other replies.