The comma , is not a valid logical operator. Try using AND or OR, depending on what you need, rows that match either one or both criteria (use OR) or only the rows that match both criteria (use AND).
You should also avoid writing dates with ambiguous formats, like the '10/15/2012 00:00:00.000'. Use either 2012-10-15T00:00:00.000 or '20121015 00:00:00.000' format. You can read Aaron Bertrand's blog for more details about dates and range queries: Bad habits to kick : mis-handling date / range queries. In this particular query and because the date has no time part, you can also use the shorter '20121015':
select *
from [dbo].[AccessFeeDetail]
where LastLoginDate >= '20121015'
AND
jobname not like 'Uptest_%' ;