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NBhatti
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MySQL (MariaDB - 10.0.16-MariaDB-1 (Debian) strange performance issues

I am running version 10.0.16-MariaDB-1 (Debian GNU/Linux 8.1 (jessie)) on Dual Xeon CPU, total 32 cores with 128 GB of RAM. This is a dedicated DB server and has been recently migrated over from Percona DB server. My configuration looks like this,

################################################################################
# DATE: 19-01-2014
# DESCRIPTION: MySQL config
# RAM: 128GB RAM dedicated server
# Connections: 1000 connections
################################################################################

[mysql]
# CLIENT #
port                           = 1979
socket                         = /var/run/mysqld/mysqld.sock

[mysqld]

## Files
back_log            = 300
open-files-limit        = 8192
#open-files             = 1024  

# GENERAL #
user                           = mysql
default-storage-engine         = InnoDB
port                           = 1979
socket                         = /var/run/mysqld/mysqld.sock
pid-file                       = /var/run/mysqld/mysql.pid

# DATA STORAGE #
datadir                        = /var/lib/mysql

# LOGGING #
log-error                      = /var/log/mysql/mysql-error.log
log-queries-not-using-indexes  = 0
slow-query-log                 = 0
slow-query-log-file            = /var/log/mysql/mysql-slow.log

## Per-Thread Buffers * (max_connections) = total per-thread mem usage
thread_stack            = 512K    #default: 32bit: 192K, 64bit: 256K
sort_buffer_size        = 2M      #default: 2M, larger may cause perf issues
read_buffer_size        = 2M      #default: 128K, change in increments of 4K
read_rnd_buffer_size        = 2M      #default: 256K                
join_buffer_size        = 2M      #default: 128K
binlog_cache_size       = 128K    #default: 32K, size of buffer to hold TX queries
## total per-thread buffer memory usage: 17664000K = 17.250GB

## Query Cache
query_cache_size        = 64M   #global buffer
query_cache_limit               = 2M    #max query result size to put in cache

## Connections
max_connections = 900   #multiplier for memory usage via per-thread buffers
max_connect_errors      = 1000  #default: 10
concurrent_insert = 2
connect_timeout         = 10    #default -5.1.22: 5, +5.1.22: 10
max_allowed_packet      = 32M   #max size of incoming data to allow

## Default Table Settings
sql_mode            = NO_AUTO_CREATE_USER

## Table and TMP settings
max_heap_table_size         = 1G    #recommend same size as tmp_table_size
bulk_insert_buffer_size         = 1G    #recommend same size as tmp_table_size
tmp_table_size                  = 1G    #recommend 1G min
tmpdir                         = /dev/shm        #Recommend using RAMDISK for tmpdir

## Table cache settings
#table_cache            = 512   #5.0.x <default: 64>
#table_open_cache       = 512   #5.1.x, 5.5.x <default: 64>

query-cache-type = 1

## Thread settings
thread_concurrency      = 32  #recommend 2x CPU cores
thread_cache_size       = 400 #recommend 5% of max_connections

## InnoDB Plugin Independent Settings
innodb_data_home_dir            = /var/lib/mysql
innodb_data_file_path       = ibdata1:128M;ibdata2:10M:autoextend
innodb_log_file_size        = 768M  #64G_RAM+ = 768, 24G_RAM+ = 512, 8G_RAM+ = 256, 2G_RAM+ = 128 
innodb_log_files_in_group   = 4 #combined size of all logs <4GB. <2G_RAM = 2, >2G_RAM = 4
innodb_buffer_pool_size     = 96G   #global buffer
innodb_additional_mem_pool_size = 8M    #global buffer
innodb_status_file          #extra reporting
innodb_file_per_table           #enable always
innodb_flush_log_at_trx_commit = 2
innodb_table_locks      = 0 #preserve table locks
innodb_log_buffer_size      = 128M  #global buffer
innodb_lock_wait_timeout = 600
#innodb_thread_concurrency = 0
innodb_commit_concurrency = 8   #recommend 4x num disks
innodb_flush_method     = O_DIRECT_NO_FSYNC    #O_DIRECT = local/DAS, O_DSYNC = SAN/iSCSI
innodb_support_xa       = 0        #recommend 0, disable xa to negate extra disk flush
innodb_fast_shutdown = 1
skip-innodb-doublewrite
skip-host-cache
# skip-name-resolve

## Binlog sync settings
## XA transactions = 1, otherwise set to 0 for best performance
sync_binlog         = 0

## TX Isolation
#transaction-isolation      = REPEATABLE-READ #REPEATABLE-READ req for ACID, SERIALIZABLE req XA

## Per-Thread Buffer memory utilization equation:
#(read_buffer_size + read_rnd_buffer_size + sort_buffer_size + thread_stack + join_buffer_size + binlog_cache_size) * max_connections

## Replication
#server_id           = 1
#log_bin             = /var/log/mysql/mysql-bin.log
#log_bin_index       = /var/log/mysql/mysql-bin.log.index
#relay_log           = /var/log/mysql/mysql-relay-bin
#relay_log_index     = /var/log/mysql/mysql-relay-bin.index
#expire_logs_days    = 10
#max_binlog_size     = 100M
#log_slave_updates   = 1
#auto-increment-increment = 2
#auto-increment-offset = 1

## Global Buffer memory utilization equation:
# innodb_buffer_pool_size + innodb_additional_mem_pool_size + innodb_log_buffer_size + key_buffer_size + query_cache_size
long_query_time = 3
innodb_checksum_algorithm=NONE
interactive_timeout = 300
wait_timeout = 40
myisam_repair_threads = 8
myisam-block-size = 8096
innodb_adaptive_hash_index = off
innodb_use_sys_malloc
innodb_sync_array_size = 4
innodb_read_ahead_threshold = 56
innodb_purge_threads = 4
innodb_adaptive_flushing = off
innodb_use_native_aio = off
innodb_random_read_ahead
optimizer_search_depth = 24
table_definition_cache = 400
table_open_cache = 2048
delay-key-write = ALL
innodb_checksum_algorithm = innodb
innodb_write_io_threads = 64
innodb_read_io_threads = 64
thread_pool_size = 16
thread_handling = pool-of-threads

innodb_disable_sort_file_cache
innodb_buffer_pool_instances = 32
innodb_adaptive_hash_index = off

[mysqldump]
quick
quote-names
max_allowed_packet      = 128M

I have multiple hosts connecting to the server and initiating queries. The problem I am facing is that randomly the DB server stops accepting connections. All connections start piling up and in around 3 or 5 seconds it comes back to normal. When I run show processlist I see a lot of connections piled up waiting on to be connected but since the DB server stops accepting connections, eventually the connection pool becomes full, no further connections are allowed.

During this blackout period, I am not able to see what's going on the DB server because i just won't give me any info even if the connection is established already. iostat -d -x 1 won't show anything unusual with the disks, CPU is also mostly idle. TCP connections piles up since the clients wants to open connections because they need to push data.

I am not able to figure out what's wrong here. Is this something specific to my DB, or the machine or the config. I need some help here on where and what to look for to identify and rectify the issue.

Thanks.