Oracle Instant Client is a light-weight software which helps to make connection to Oracle Database. It containsrun OCI, JDBCOBDBC, SQL*PLUS and SDKPro*C, JDBC without installing full Oracle client. In In other hand the Oracle Call Interface (OCI) is an application programming interface (API) that allows applications written in C to interact with one or more Oracle Servers.
For details:
What is Oracle's instant client and how do I install it?
Introduction to Oracle Call Interface