for the users that do not have a login in the server follow this link:
--technet article on orphaned users
Report on failed users - shows all SQL users on server
USE [<database>]
EXEC sp_change_users_login 'REPORT'
--SQL 2000 and earlier
USE [<database>]
EXEC sp_change_users_login 'Auto_Fix', 'MyUser'
--SQL 2005 onwards
USE [<database>]
ALTER USER [MyUser] WITH LOGIN = [MyUser]
--to find database users (windows accounts) without Server login
select users.name, logins.name
from master..syslogins logins
right join sysusers users on logins.sid = users.sid
where logins.sid is null
and issqlrole <> 1
and isapprole <> 1
and (users.name <> 'INFORMATION_SCHEMA'
and users.name not in ('guest', 'dbo', 'sys', 'system_function_schema'))
a number of process running for a long time that are blocking and causing other issues
for this I recommend the procedure called sp_whoisactivesp_whoisactive