It looks like the database was trying to updateselect 30593 rows, and maybe it was taking a long time. Since no keys are identified in the 'explain', make user uuser_id and file_id have indexes on them. Postingadd an index to file_name_eng since it is in the order clause.
As RolandoMySQLDBA suggested, carefully evaluate if you really need a select * there. Add LIMIT clauses and paging of results if you are showing this to a user somewhere (and not just dumping all records to a file)
Also be aware of "show createMyISAM table files"locks. Long running selects will helpblock updates as RolandoMySQLDBA said. I don't think you have to convert to InnoDB as a first step though. Large MyISAM tables work OK if you are careful to use indexes and don't do "SELECT *" queries without a LIMIT, or a WHERE clause at least.