We recently upgraded from SQL 2016 SP1 build 4466 to SP2 build 5201 (CU2 GDR) on an AG.
On one server an analyst was deploying SSIS using Visual Studio Enterprise 2015 (version 14.0.25431.01 Update 3 and MS. NET framework 4.7.02558).
Since the SQL upgrade they get this error message:
Failed to deploy project. For more information , query the operation_messages view for the operation identifier '777'. (Microsoft SQL Server, Error: 27203)
Querying the operations_messages table in the SSISDB database for 777 I get this message:
Failed to deploy the project. Fix the problems and try again later.:Cannot use SAVE TRANSACTION within a distributed transaction.
That message appeared as fixed in SP2 CU1 in this KB https://support.microsoft.com/en-us/help/4092554/fix-cannot-use-save-transaction-within-a-distributed-transaction-when
The analyst says she gets the same error if she uses Management Studio and the IS Deployment Wizard.