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I've made this query

SELECT id,name,iupac_name,inchi_key,molecular_weight,molecular_formula,exact_molecular_mass
    FROM compound
    WHERE name LIKE '%quer%'
    OR iupac_name LIKE '%quer%'
    OR inchi_key LIKE '%quer%'
    OR inchi_key IN( SELECT inchi_key FROM compound_synonyms WHERE name LIKE '%quer%')

that took 0.3563 seconds to show result through phpmyadmin in my local machine and took 0.1117 seconds in digital ocean vps.

But the same query took 24+ minutes in another vps.

Does anyone can help me to find out the problem?

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Several things make the query slow:

  • Leading wildcard in LIKE. (See below)
  • OR -- One workaround is with UNION.
  • IN ( SELECT ... ) -- This one is version-dependent; what version is each machine running?

The first two can be alleviated by using a FULLTEXT(name, iupac_name, inchi_key) and MATCH(name, iupac_name, inchi_key) AGAINST('quer*' IN BOOLEAN MODE).

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