We are using Amazon Web Service's MySQL 5.7.26 with 4 read-only replicas. After some Alter Table operations we have found that the replication stops working. The symtoms are great replica lag that is only solved after rebooting the databases.
The problema has occurred serveral times. Sometimes even with very small tables (1000 records). This is problematic as it reduces our window to do changes that ordinarly would be done during working hours.
P.S: the engine is MySQL Community