It was brought to my attention that our (Hitachi) SAN handles data in 42MB blocks. It is tiered storage so each block is evaluated when the director makes decisions as to when it should promote/demote storage to faster/slower storage. In the absence of having the political weight to "pin" particular LUNs to particular tiers I am trying to do all I can to set up my SQL Server (2008 R2 Enterprise) instance for success. 

As such, I was wondering if there would be any benefit/detriment to changing my file sizes and file growth sizes to multiples of 42? An example database would be `SIZE=57886MB` with a `FILEGROWTH=5124MB`.

I see the potential for extra reads (since (42*1024)/8 = 8601.6, but (42*1024)/64 = 672) but I'm not sure I'm fully grasping all of the concepts here.