You have to concentrate on Memory, Disk IO and CPU utilization to balance out your environment.
Best is to start collecting and dumping the results in a utility database and to give you a good baseline using sql agent on a scheduled basis.
Alternatively, you can use Performance data collector (applies to sql server 2008 and up)
MEMORY:
You can look into buffer pool usage (what databases are occupying more space in buffer pool ?)
From :Performance issues from wasted buffer pool memory
SELECT
(CASE WHEN ([database_id] = 32767)
THEN N'Resource Database'
ELSE DB_NAME ([database_id]) END) AS [DatabaseName],
COUNT (*) * 8 / 1024 AS [MBUsed],
SUM (CAST ([free_space_in_bytes] AS BIGINT)) / (1024 * 1024) AS [MBEmpty]
FROM sys.dm_os_buffer_descriptors
GROUP BY [database_id];
GO
DISK IO:
In terms of Disk IO, you need to move away the mdf/ldf files having the most disk IO to a better/faster LUN/Array :
From : How to examine IO subsystem latencies from within SQL Server
SELECT
[ReadLatency] =
CASE WHEN [num_of_reads] = 0
THEN 0 ELSE ([io_stall_read_ms] / [num_of_reads]) END,
[WriteLatency] =
CASE WHEN [num_of_writes] = 0
THEN 0 ELSE ([io_stall_write_ms] / [num_of_writes]) END,
[Latency] =
CASE WHEN ([num_of_reads] = 0 AND [num_of_writes] = 0)
THEN 0 ELSE ([io_stall] / ([num_of_reads] + [num_of_writes])) END,
[AvgBPerRead] =
CASE WHEN [num_of_reads] = 0
THEN 0 ELSE ([num_of_bytes_read] / [num_of_reads]) END,
[AvgBPerWrite] =
CASE WHEN [num_of_writes] = 0
THEN 0 ELSE ([num_of_bytes_written] / [num_of_writes]) END,
[AvgBPerTransfer] =
CASE WHEN ([num_of_reads] = 0 AND [num_of_writes] = 0)
THEN 0 ELSE
(([num_of_bytes_read] + [num_of_bytes_written]) /
([num_of_reads] + [num_of_writes])) END,
LEFT ([mf].[physical_name], 2) AS [Drive],
DB_NAME ([vfs].[database_id]) AS [DB],
[mf].[physical_name]
FROM
sys.dm_io_virtual_file_stats (NULL,NULL) AS [vfs]
JOIN sys.master_files AS [mf]
ON [vfs].[database_id] = [mf].[database_id]
AND [vfs].[file_id] = [mf].[file_id]
-- WHERE [vfs].[file_id] = 2 -- log files
-- ORDER BY [Latency] DESC
-- ORDER BY [ReadLatency] DESC
ORDER BY [WriteLatency] DESC;
GO
Also refer to Leveraging sys.dm_io_virtual_file_stats
CPU:
From : Brent's answer
SELECT total_worker_time/execution_count AS AvgCPU
, total_worker_time AS TotalCPU
, total_elapsed_time/execution_count AS AvgDuration
, total_elapsed_time AS TotalDuration
, (total_logical_reads+total_physical_reads)/execution_count AS AvgReads
, (total_logical_reads+total_physical_reads) AS TotalReads
, execution_count
, SUBSTRING(st.TEXT, (qs.statement_start_offset/2)+1
, ((CASE qs.statement_end_offset WHEN -1 THEN datalength(st.TEXT)
ELSE qs.statement_end_offset
END - qs.statement_start_offset)/2) + 1) AS txt
, query_plan
FROM sys.dm_exec_query_stats AS qs
cross apply sys.dm_exec_sql_text(qs.sql_handle) AS st
cross apply sys.dm_exec_query_plan (qs.plan_handle) AS qp
ORDER BY 1 DESC
A gold mine of DMV related queries : SQL Server Diagnostic Information Queries for September 2014
For completeness, if you are using sql server 2012, you can use the system health reporting dashboard for Visualizing sp_server_diagnostics results.
sys.dm_exec_query_stats
and cross apply withsys.dm_exec_sql_text